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Hepatocellular carcinoma (HCC)


Risk factors for HCC

  • Hepatitis B or hepatitis C infection.
  • Alcoholism.
  • HH
  • PBC > PSC
  • Alpha-1-antitrypsin deficiency
  • Steroids


Investigations in HCC

  • Ultrasound scan (USS)
    • First line and very sensitive
  • Alpha-fetoprotein (AFP)
    • If a >2 cm mass is detected on USS and AFP is also raised, this is diagnostic
  •  CT
    • Can look for local spread and CT of the thorax can look for metastases.
    • MRI or FNA if diagnosis still in doubt


Prognosis in HCC


Click here to download free teaching notes on Decompensated CLD: Hepatocellular carcinoma (HCC)

Perfect revision for medical students, finals, OSCEs and MRCP PACES