Common hepatosplenomegaly exam questions for medical finals, OSCEs and MRCP PACES
Question 1.
What are the haematological causes of hepatosplenomegaly?
- Leukaemias (AML, CML, ALL, CLL)
- Lymphomas
- Myelofibrosis
- Myeloproliferative disease
- Essential thrombocytopenia, polycythaemia, primary myelofibrosis, CML
- Haemolytic anaemias
- Hb disorders: Thalassaemia, sickle cell disease (eventually leads to splenic atrophy)
- Red cell structure: Spherocytosis/elliptocytosis
- Enzyme: G6PD deficiency, pyruvate kinase deficiency
See questions on hepatomegaly and splenomegaly for further questions