Lewy Body Dementia (LBD or DLB)

  • Named after Frederic Lewy
  • Characterised by the presence of Lewy Body-like inclusions within neurones
  • Gradual death and decline of brain cells
  • Low-levels of acetylcholine and dopamine observed
  • Symptoms
    • Akin to a combination of Alzheimer’s and Parkinson’s Disease
    • Marked fluctuation may occur throughout the day
    • Disrupted sleep patterns
    • Hallucinations (particularly visual)
    • Parkinsonism movement disorders, but less-susceptible to treatment with L-Dopa
  • Diagnosis is clinical, though the classical distinguishing features (hallucinations etc…) may not always be present
    • Can be difficult to distinguish LBD from Alzheimer’s with Parkinson’s Disease

 

Click here to learn about the diagnosis and management of dementia

Click here to learn about cognitive assessment in dementia